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This routes biologics and peptides directly into the CNS, bypassing first-pass hepatic metabolism and avoiding the highly selective BBB entirely

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The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-alpha Expression in Macrophages

Roughly 20 years ago (give or take) peptides first started making their way into the wellness and beauty universe via skincare, thanks to their knack for boosting collagen and softening the visible signs of aging